ODCs

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2 OMIM references -
2 associated genes
10 signs/symptoms

PROTEIN INTERACTIONS: 1

3 associated genes
No signs/symptoms info

Isolated 3-methylcrotonyl-CoA carboxylase deficiency

Dedifferentiated liposarcoma


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MCCC2	(0.63)	MDM2

Citations in the biomedical literature:

Isolated 3-methylcrotonyl-CoA carboxylase deficiency		Dedifferentiated liposarcoma
	Synonym(s): - 3-methylcrotonylglycinuria - MCC deficiency - MCCD		Synonym(s): - DDLS

	Classification (Orphanet): - Inborn errors of metabolism - Rare genetic disease		Classification (Orphanet): - Rare oncologic disease

	Classification (ICD10): - Endocrine, nutritional and metabolic diseases -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic

	External references: 2 OMIM references - 1 MeSH reference: C535308		External references: No OMIM references No MeSH references

Isolated 3-methylcrotonyl-CoA carboxylase deficiency
	Very frequent - Hypoglycemia - Hypotonia - Metabolic anomalies - Organic acid metabolism anomalies Frequent - Failure to thrive / difficulties for feeding in infancy / growth delay - Hyperammonemia - Movement disorder Occasional - Cerebral vascular anomalies - Hypertonia / spasticity / rigidity / stiffness - Respiratory distress / dyspnea / respiratory failure / lung volume reduction
Dedifferentiated liposarcoma
(no data available)